منابع مشابه
The First Experience of Ex-Vivo Lung Perfusion (EVLP) in Iran: An Effective Method to Increase Suitable Lung for Transplantation
BACKGROUND Although lung transplantation is a well-accepted treatment for end-stage lung diseases patients, only 15%-20% of the brain-dead donors' lungs are usable for transplantation. This results in high mortality of candidates on waiting lists. Ex-vivo lung perfusion (EVLP) is a novel method for better evaluation of a potential lung for transplantation. OBJECTIVE To report the first experi...
متن کاملMethod of Isolated Ex Vivo Lung Perfusion in a Rat Model: Lessons Learned from Developing a Rat EVLP Program
The number of acceptable donor lungs available for lung transplantation is severely limited due to poor quality. Ex-Vivo Lung Perfusion (EVLP) has allowed lung transplantation in humans to become more readily available by enabling the ability to assess organs and expand the donor pool. As this technology expands and improves, the ability to potentially evaluate and improve the quality of substa...
متن کاملEx vivo lung perfusion in Brazil
OBJECTIVE To evaluate the use of ex vivo lung perfusion (EVLP) clinically to prepare donor lungs for transplantation. METHODS A prospective study involving EVLP for the reconditioning of extended-criteria donor lungs, the criteria for which include aspects such as a PaO2/FiO2 ratio < 300 mmHg. Between February of 2013 and February of 2014, the lungs of five donors were submitted to EVLP for u...
متن کاملEx vivo lung perfusion: initial Brazilian experience* Perfusão pulmonar ex vivo: experiência nacional inicial
In the last 20 years, lung transplantation has become the standard treatment for patients with end-stage lung disease. However, less than 20% of the donor lungs available for transplant are actually usable. This disparity between the growing number of recipients and the small number of donors has resulted in increased mortality among lung transplant candidates on waiting lists. Strategies such ...
متن کاملAntagonizing reactive oxygen species during ex vivo lung perfusion.
TO THE EDITOR: The stop of flow (ischemia) would be interpreted as membrane depolarization, through the inhibition of KATP channels, leading to activation of NADPH oxidase, leading to increased reactive oxygen species (ROS) production (1). The resultant ROS are claimed to be an effective mediator for ischemic preconditioning (IPC), as proved by the observation that the presence of antioxidants ...
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ژورنال
عنوان ژورنال: Current Respiratory Care Reports
سال: 2013
ISSN: 2161-332X
DOI: 10.1007/s13665-013-0058-9